Contribution de la neurochirurgie à l'étude de la libération de GnRH chez la brebis

This article describes the main surgical approaches used in sheep to measure the release of GnRH, the hypothalamic hormone controlling the reproductive function. Two methods have been developed in this species: the hypophyseal portal blood collection and the sampling of cerebrospinal fluid from the third ventricle of the brain. These methods have demonstrated that GnRH is secreted during very short periods of time, called pulses. The GnRH pulses are the link between the neuronal signal and the